Search results for "REACTION-TIME VARIABILITY"

showing 2 items of 2 documents

Performance variability, impulsivity errors and the impact of incentives as gender-independent endophenotypes for ADHD

2010

Background:Attention-deficit hyperactivity disorder (ADHD) is one of the most common and highly heritable child psychiatric disorders. There is strong evidence that children with ADHD show slower and more variable responses in tasks such as Go/Nogo tapping aspects of executive functions like sustained attention and response control which may be modulated by motivational factors and/or state-regulation processes. The aim of this study was (1) to determine if these executive functions may constitute an endophenotype for ADHD; (2) to investigate for the first time whether known modulators of these executive functions may also be familial; and (3) to explore whether gender has an impact on thes…

MaleMedizinCHILDRENNeuropsychological TestsDevelopmental psychology0302 clinical medicineDevelopmental and Educational Psychologyfalse alarmsChild10. No inequalitystate regulationAD/HDATTENTION-DEFICIT/HYPERACTIVITY DISORDER05 social sciencesEXECUTIVE FUNCTIONSNeuropsychologyCognitionExecutive functionsendophenotypePsychiatry and Mental healthPhenotypeFemalemedicine.symptomAttention-deficit hyperactivity disorderPsychologyRESPONSE-INHIBITION050104 developmental & child psychologyreaction-time variabilityAdolescentincentivesDEFICIT HYPERACTIVITY DISORDERQUESTIONNAIREMOTOR CONTROLImpulsivityArticle03 medical and health sciencesSex Factorsmental disordersReaction TimemedicineCriterion validityHumansAttention deficit hyperactivity disorderADHD0501 psychology and cognitive sciencesddc:610Medizinische Fakultät » Universitätsklinikum Essen » LVR-Klinikum Essen » Klinik für Psychiatrie Psychosomatik und Psychotherapie des Kindes- und JugendaltersSiblingMotivationmedicine.diseaseDisruptive Impulse Control and Conduct Disordersexecutive functionAttention Deficit Disorder with HyperactivityEndophenotypePediatrics Perinatology and Child HealthSUSTAINED ATTENTIONCRITERION VALIDITYCognition Disorders030217 neurology & neurosurgery
researchProduct

Polygenic association between attention-deficit/hyperactivity disorder liability and cognitive impairments.

2022

AbstractBackgroundA recent genome-wide association study (GWAS) identified 12 independent loci significantly associated with attention-deficit/hyperactivity disorder (ADHD). Polygenic risk scores (PRS), derived from the GWAS, can be used to assess genetic overlap between ADHD and other traits. Using ADHD samples from several international sites, we derived PRS for ADHD from the recent GWAS to test whether genetic variants that contribute to ADHD also influence two cognitive functions that show strong association with ADHD: attention regulation and response inhibition, captured by reaction time variability (RTV) and commission errors (CE).MethodsThe discovery GWAS included 19 099 ADHD cases …

cognitionTrastorns per dèficit d'atenció amb hiperactivitat en els infantsMedizinSocial SciencesGenome-wide association studyAttention deficit disorder with hyperactivity in children3202 Applied Psychology2738 Psychiatry and Mental Health0302 clinical medicineAtencióDUPLICATIONS2.1 Biological and endogenous factorsPsychologyAetiologyGenetic riskChildPOPULATIONApplied PsychologyResponse inhibitionPsychiatryREACTION-TIME VARIABILITYCognition10058 Department of Child and Adolescent PsychiatryinhibitionPsychiatry and Mental healthPhenotypeMental Healthpolygenic risk scoresreaction time variabilityCognicióPublic Health and Health Services/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingTrastorns per dèficit d'atenció amb hiperactivitat en els adultsRESPONSE-INHIBITIONClinical psychologyAdultAdolescentDEFICIT HYPERACTIVITY DISORDER610 Medicine & healthGENETIC RISKbehavioral disciplines and activitiesYoung Adult03 medical and health sciencesWORKING-MEMORYSDG 3 - Good Health and Well-beingmental disordersReaction TimeGeneticsmedicineHumansAttention deficit hyperactivity disorderADHDCognitive DysfunctionGENOME-WIDE ASSOCIATIONAssociation (psychology)business.industryPreventionHuman GenomeNeurosciencesGenetic variantsPERFORMANCEmedicine.diseaseAttention Deficit Hyperactivity Disorder (ADHD)030227 psychiatryattentionAttention Deficit Disorder with HyperactivityInhibicióCase-Control StudiesAttention deficit disorder with hyperactivity in adultsPolygenic risk scorebusiness030217 neurology & neurosurgeryGenome-Wide Association StudyPsychological medicine
researchProduct